![]() The POC testing analyzer i-STAT is a reliable alternative to the traditional blood gas analyzers and provides marginal improvement in turnaround time when compared with the service received from the PICU/NICU laboratory. ![]() The regression analysis (slope and correlation coefficient) of the results from instruments run with and without QC samples gave results close to 1, indicating that there is no need to run additional quality control (QC). Electrolytes are also measured during arterial blood gas analysis, but are traditionally rarely trusted for clinical decision-making because of the dearth of published research about the same. A further study was made to assess whether routine quality control (QC) samples are necessary when using the i-STAT system. The operational cost of iSTAT and other similar equipment is a major deterrent to their utilization in developing systems of health care. There was no significant difference in the results when operated by PICU/NICU nurses or laboratory personnel. Patients' results from the i-STAT correlated well with the Ciba Coming 288 blood gas analyzer (r = 0.99 for pH, pCO2 and pO2 and 0.95 to 0.99 for Na+ and K+) with the exception of iCa2+ (r = 0.73). Comparison of the i-STAT and the Ciba Coming 288 blood gas analyzer was assessed by split sample measurement. Linearity studies showed good linearity over the five different concentrations tested. Using whole blood studies the precision data gave %CVs that were < 3.5 for all the analytes. To create it, innovators from Abbott's research and development (R&D) team spent six years designing prototype. Except for pO2, the %CVs were < 3.0 for all the analytes (pH, pCO2, Na+, K+ and iCa2+) at all the three concentrations. As a handheld, portable blood testing device available by prescription, it can provide results within minutes virtually anywhere, from hospitals and nursing homes to the sidelines of sporting events. The system was evaluated for imprecision and linearity using three concentrations of aqueous standards. The reliability of the i-STAT system when performed by non-laboratory personnel was assessed. Comparison of patients' samples analyzed by the i-STAT system and the Ciba Coming 288 blood gas analyzer were performed. ![]() The i-STAT system was evaluated for imprecision, necessity of running quality control and accuracy. With over 50,000 handhelds placed in high-acuity settings worldwide–including over 1,800 hospitals-and over 35 million test cartridges produced annually, the i-STAT System is trusted to provide lab-quality results.To evaluate the Point-of-Care (POC) i-STAT system for measuring blood gases (pH, pCO2, pO2) and whole blood electrolytes (sodium, Na+, potassium, K+ and ionized calcium, iCa2+) in the neonatal and pediatric intensive care units.
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